Home Head & Hair Scientists Discover Baldness Gene



Scientists Discover Baldness Gene PDF Print E-mail
User Rating: / 0

Scientists say they've uncovered a gene that causes a rare but distressing form of childhood baldness, a finding that could help the quest to treat hair loss.


Mutation in a gene called APCDD1 plays a key role in a disease called hereditary hypotrichosis simplex (HHS), which causes progressive hair loss starting in childhood.



Hair follicles start to shrink or narrow, causing the thick hair on the scalp to be replaced by 'peach fuzz' of thin, fine hair.

APCDD1, which is located on Chromosome 18, was found thanks to a trawl through the genome of several families from Pakistan and Italy where HHS goes back generations.

Lead author Angela Christiano, a professor of dermatology at Columbia University Medical Centre, New York, dampened expectations for bald men hoping that a drug for hair regrowth now lies in sight.

Male pattern baldness also entails follicular shrinkage, but the process is more complex and not directly comparable to HHS, she said on Wednesday.

Among people with HSS, a flawed version of APCDD1 disrupts a signaling pathway in which genes instruct proteins to turn hair growth on or off.

This so-called Wnt pathway has been extensively explored in lab mice, so finding that it also exists among humans is an important step forward in figuring out the causes of baldness.

"Furthermore, these findings suggest that manipulating the Wnt pathway may have an effect on hair follicle growth - for the first time, in humans," said Christiano.

The paper appears in the British science journal Nature.


Stop Male Hair Loss In 3-7 Days
10 Minute Method Makes Hair Look Fuller & Healthier In Minutes. Stop Male Hair Loss In 3-7 Days & Grow Hair Back Naturally.

Table Of Contents:

Beauty  - Fitness  - Health  - Mind  - Nutrition  - Weight Control  - FAQ

Social Links:

Facebook  - Twitter  - MySpace  - Squido  - WikiSpaces

Copyright © 2011 Abundant Fitness. All Rights Reserved.

Stop Male Hair Loss In 3-7 Days
10 Minute Method Makes Hair Look Fuller & Healthier In Minutes. Stop Male Hair Loss In 3-7 Days & Grow Hair Back Naturally.

Freedom From GOUT Now!
Long-Suffering Wife of Former Gout Victim Challenged The Uncaring Drug Companies & Makes A Shocking Discovery That Cured Her Husband Once And For All…
Rediscover Your Vision Without Glasses, Contacts or Surgery
Optometrists FORCED To Agree With New PROVEN Method To Rediscover Your 20/20 Perfect Vision Without Use Of Expensive Glasses, Experimental Drugs or Dangerous Eye Surgery
You Can Have Thin, Sexy Thighs & Legs
Whether it's fair or not, men judge women by their bodies. You Are Just Moments Away From Learning How Models, Actresses and Every Day Women Can Achieve Head Turning, Slender, Sexy, Shapely Thin Thighs That Turn Men's Heads When You Walk By!
Cancer & Health- It's All About The Cell.
Discover The Truth About Cancer And How To Eliminate Sickness And Disease Naturally By Health Expert Dr. Thompson!